The world of nutritional supplements is constantly evolving. Every year, new products and ingredients emerge, promising to support health, vitality and longevity in innovative ways. In this article, we explore the top emerging supplements expected to gain prominence in 2025. 

These insights are provided by Vivere's Head of Nutrition, Yusra Serdaroglu Aydin, a registered dietitian with a background in nutrition, food engineering and culinary arts. Her approach is grounded in science and shaped by a strong understanding of personalised nutrition and the human microbiome. Whether you are a health enthusiast or someone seeking to optimise wellbeing through nutrition, this article offers evidence-based guidance on the most promising supplements to watch.

• Nicotinamide riboside and nicotinamide mononucleotide boost NAD⁺ for cellular energy and healthy ageing, yet at‑home NAD injection pens deliver NAD⁺ more efficiently, bypassing digestion.

• New trends in gut health supplements include postbiotics and psychobiotics, expanding beyond traditional prebiotics and probiotics.

• Adaptogenic herbs like ashwagandha, rhodiola and cordyceps help improve stress resilience and cognitive performance.

• Immune support supplements like elderberry, colostrum, astaxanthin and medicinal mushroom extracts such as reishi are now gaining more attention.

• Supplements supporting metabolic health, such as iodine, NAC and berberine, are gaining recognition for their role in overall well-being.

Supplements can be valuable tools for filling nutritional gaps and supporting specific health goals. However, they should always complement a balanced diet and healthy lifestyle rather than replace them. Scientific advances in biochemistry, microbiome research and nutrigenomics are shaping supplements that not only meet basic nutritional needs but also optimise metabolism, immune function and cellular repair processes linked to healthy ageing.

Nicotinamide adenine dinucleotide (NAD+) is a vital coenzyme involved in energy metabolism and DNA repair. NAD+ levels naturally decline with age, affecting cellular function and vitality.

Key supplements for boosting NAD+ include:

• Nicotinamide Riboside (NR) and Nicotinamide Mononucleotide (NMN): Precursors that support the body's natural NAD+ production and mitochondrial function [1].

• At-Home NAD Injection Pens: These offer a more direct and efficient method of increasing NAD+ levels compared to oral precursors. Injection pens bypass digestive degradation, delivering NAD+ rapidly into the bloodstream for faster and potentially stronger effects [2]. Vivere offers a highly effective at-home NAD+ injection pen that you can buy online, for only £10.79 per dose.

Combining these supplements with lifestyle factors such as intermittent fasting and exercise can further enhance NAD+ levels and support healthy ageing.

Gut health is fundamental to overall wellbeing, with the microbiome influencing digestion, immunity and even mood. Traditional gut supplements have focused on:

• Prebiotics: Non-digestible fibres that nourish beneficial gut bacteria.

• Probiotics: Live beneficial bacteria strains introduced into the gut.

Emerging trends now include:

• Postbiotics: Metabolic by-products from gut bacteria that support gut barrier integrity and immune modulation.

• Psychobiotics: Specific probiotics that influence mental health through the gut-brain axis [3].

Personalised testing may help determine which supplements or combinations offer the greatest benefit based on individual microbiome profiles.

Adaptogenic herbs are gaining popularity for their ability to improve the body's response to physical and mental stress. Notable adaptogens for 2025 include:

• Ashwagandha: Helps reduce cortisol levels and improve sleep quality [4].

• Rhodiola: Supports mental stamina and reduces fatigue [5].

• Cordyceps: Enhances physical performance and immune function [6].

Using high-quality, standardised adaptogens as part of a holistic stress management strategy can improve resilience and well-being.

Immune health supplements are evolving to offer targeted support beyond basic vitamins and minerals:

• Elderberry: Known for its antiviral and antioxidant properties [7].

• Colostrum: Rich in antibodies that support gut-associated lymphoid tissue [8].

• Astaxanthin: A potent antioxidant with anti-inflammatory effects [9].

• Medicinal Mushroom Extracts (Reishi): Contain beta-glucans that activate immune cells like macrophages and natural killer cells [10].

Combining these supplements with a nutrient-rich diet and healthy habits strengthens immune resilience.

Supplements are increasingly recognised for their role in supporting metabolic function, which is vital for energy regulation and disease prevention:

• Iodine: Essential for thyroid hormone production and metabolic rate [11].

• N-Acetylcysteine (NAC): Precursor to glutathione, aiding detoxification and antioxidant defence [12].

• Berberine: Plant-based compound shown to improve insulin sensitivity and blood sugar control, may help with weight loss as well [13].

Integrating these supplements with personalised advice and lifestyle modifications can promote metabolic health.

Nootropic supplements support brain function, improving memory, focus and mental clarity. Key ingredients to watch include:

• Lion’s Mane Mushroom: Stimulates nerve growth factor and neurogenesis [14].

• L-Theanine: An amino acid promoting relaxation without sedation [15].

• Ginkgo Biloba: Enhances cerebral blood flow and cognitive processing speed [16].

Optimal cognitive health is best achieved by combining nootropics with proper sleep, nutrition and stress management.

Emerging supplements in 2025 represent a blend of traditional wisdom and modern science. From NAD+ boosters and gut health innovations to adaptogens and metabolic enhancers, these products offer new ways to optimise wellbeing. A well-planned supplement regimen can amplify energy, cognitive function, mood and overall resilience, but it should sit alongside a balanced diet rather than replace it. Always consult a qualified healthcare provider before starting any new supplement, as the most effective results come from products chosen and dosed to meet personal needs and goals. While some ingredients may ride marketing waves, selecting scientifically supported options ensures you invest in benefits that last.

Vivere helps you take control of your health with personalised insights from state-of-the-art gut microbiome testing, nutritional guidance, science-backed supplements and expert support. Join Vivere today and start living better, for longer.

[1] NAD+ Precursors Nicotinamide Mononucleotide (NMN) and Nicotinamide Riboside (NR): Potential Dietary Contribution to Health - PMC

[2] Medication Routes of Administration - NLM

[3] Innovative Interventions: Postbiotics and Psychobiotics in Neurodegenerative Disease Treatment - PMC

[4] Withania somnifera (Ashwagandha) supplementation: a review of its mechanisms, health benefits, and role in sports performance - PMC

[5] The Effectiveness of Rhodiola rosea L. Preparations in Alleviating Various Aspects of Life-Stress Symptoms and Stress-Induced Conditions—Encouraging Clinical Evidence - PMC

[6] Cordyceps militaris improves tolerance to high intensity exercise after acute and chronic supplementation - PMC

[7] Elderberries—A Source of Bioactive Compounds with Antiviral Action - PMC

[8] A Review: The Effect of Bovine Colostrum on Immunity in People of All Ages - MDPI

[9] Anti-Oxidant and Anti-Inflammatory Effects of Astaxanthin on Gastrointestinal Diseases - PMC

[10] Exploring the Potential Medicinal Benefits of Ganoderma lucidum: From Metabolic Disorders to Coronavirus Infections - PMC

[11] Thyroid function and iodine intake: global recommendations and relevant dietary trends - Nature

[12] Existing and potential therapeutic uses for N-acetylcysteine: The need for conversion to intracellular glutathione for antioxidant benefits - Science Direct

[13] The effect of Berberine on weight loss in order to prevent obesity: A systematic review - Science Direct

[14] The Acute and Chronic Effects of Lion’s Mane Mushroom Supplementation on Cognitive Function, Stress and Mood in Young Adults: A Double-Blind, Parallel Groups, Pilot Study - PMC

[15] In Search of a Safe Natural Sleep Aid - NLM

[16] Examining Brain-Cognition Effects of Ginkgo Biloba Extract: Brain Activation in the Left Temporal and Left Prefrontal Cortex in an Object Working Memory Task - Wiley