What Your Microbiome Age Says About You?

Biological Ageing

15 August 2025

Understanding your health goes beyond counting calories or steps. One of the most insightful measures of your overall well-being lies deep within your gut. Your microbiome age, an estimate of your biological age based on the state of your gut microbiome, may offer valuable insight about your long-term health, resilience and risk of chronic illness.

In this article, we explore what microbiome age is, how it’s measured, why it matters and what it can reveal about your lifestyle and health choices. The insights provided here are from Yusra Serdaroglu Aydin, Vivere’s Head of Nutrition. Yusra is a registered dietitian with a background in nutrition, food engineering and culinary arts. Her approach is grounded in science and shaped by a strong understanding of personalised nutrition and the human microbiome.

Key Takeaways

Here are the five biggest takeaways from this article about your microbiome age and what it says about you:

  • Your microbiome age can differ from your chronological age and may reflect how well your gut is ageing.

  • A younger microbiome age is often linked to better gut health, lower inflammation and stronger immunity.

  • Diet, lifestyle and stress all play significant roles in shaping your microbiome and influencing its age.

  • Testing your microbiome age can provide early indicators of disease risk and help guide personalised health strategies.

  • Small, consistent changes to your diet and habits can support a healthier, more youthful gut microbiome.

What is microbiome age?

Your microbiome age refers to an estimation of your biological age based on the composition and diversity of microbes living in your gut. It is calculated using data from stool samples, which are analysed to identify patterns associated with ageing.

Unlike your chronological age, the number of years you’ve been alive, your microbiome age provides insight into how your body is functioning on a cellular level. A “younger” microbiome age may indicate a healthier gut, while an “older” one could suggest an imbalance or reduced resilience in your microbiota.

Researchers have found that a balanced, diverse gut microbiome is associated with better health outcomes, including improved immune function, reduced inflammation and enhanced mental well-being. As we age, microbial diversity tends to decline, which may contribute to a range of age-related diseases [1] [2].

How is microbiome age measured?

Measuring microbiome age involves analysing the bacterial composition of your gut through advanced sequencing technologies. These tests identify the presence and abundance of various microbial species and compare them to population data associated with different age groups [3] [4].

Factors such as microbial diversity, the presence of specific beneficial or harmful bacteria, and overall microbial balance are taken into account. Based on this analysis, a biological age is estimated, which may be younger, older or roughly the same as your actual age [5] [6] [7].

At Vivere, gut microbiome testing provides more than just a number. It offers a personalised report with actionable insights, highlighting areas of strength and potential concern, alongside tailored recommendations to help rebalance and support your gut health.

Why microbiome age matters

A younger microbiome age is not just a vanity metric, it’s often a marker of resilience and lower disease risk. Several studies have shown that people with microbiomes that appear “younger” tend to experience better metabolic health, stronger immune responses and even enhanced cognitive performance.

On the other hand, an older microbiome age may be linked to inflammation, digestive issues, reduced immune defence and a greater likelihood of developing conditions such as type 2 diabetes, obesity and cardiovascular disease. It may also impact mental health, with research increasingly pointing to a gut-brain connection affecting mood, anxiety and sleep [8] [9] [10] [11] [12] [13].

Understanding your microbiome age gives you a proactive way to assess your health and take steps towards improvement. While we cannot control our chronological age, we can influence our biological and microbiome age through informed lifestyle choices.

What influences your microbiome age?

Numerous lifestyle and environmental factors contribute to the ageing of the gut microbiome:

Diet

A fibre-rich, plant-based diet supports microbial diversity and feeds beneficial bacteria. Processed foods, high sugar intake and low fibre diet are associated with inflammation and microbiome ageing [14] [15] [16] [17] [18].

Stress

Chronic stress affects gut permeability and microbiota balance. High stress levels can lead to dysbiosis, an imbalance of gut bacteria, which contributes to premature microbiome ageing [19] [20].

Sleep

Poor sleep quality or irregular sleep patterns can alter gut microbiota composition. A consistent sleep routine supports circadian rhythms, which in turn benefit microbial health [21] [22] [23] [24] [25].

Exercise

Regular physical activity has been shown to improve gut diversity and support the growth of beneficial microbes [26] [27] [28].

Antibiotics and Medications

Frequent or unnecessary use of antibiotics can disrupt gut microbiota, wiping out both harmful and helpful bacteria. This can accelerate microbiome ageing if not addressed through proper recovery strategies [29] [30] [31] [32].

Alcohol and Smoking

Excessive alcohol consumption and smoking are linked to inflammation and poor microbial diversity, both of which can make your gut microbiome appear older than your years [33] [34] [35] [36] [37].

Can you make your microbiome younger?

The good news is that microbiome age is not fixed. With the right changes, you can often reverse patterns associated with microbiome ageing and support a more youthful gut environment.

Simple, evidence-based actions include:

  • Increasing your intake of prebiotic foods such as oats, garlic, leeks, onions and bananas

  • Adding fermented foods like kefir, yoghurt, kimchi or sauerkraut to your meals

  • Reducing processed foods and added sugars

  • Ensuring sufficient fibre from a range of fruits, vegetables, legumes and whole grains

  • Staying physically active and managing stress through mindfulness or relaxation techniques

These changes may not only support your gut health but also contribute to better energy, sleep, immunity and mood.

The role of personalised nutrition

What works for one person may not work for another. This is where personalised nutrition comes in; an approach that uses data from your own body to guide dietary and lifestyle choices.

By understanding your microbiome age and the specific composition of your gut bacteria, you can adopt changes that are tailored to your needs. This is far more effective than following general dietary advice, as it accounts for your unique microbiome, health status and goals.

Vivere offers personalised microbiome reports and guidance, ensuring every recommendation is based on real science and designed to support your long-term health [38] [39] [40] [41].

Microbiome age and long-term health

Your microbiome plays a crucial role in everything from digestion to immune defence and mental health. By monitoring and supporting your microbiome age, you’re investing in more than just your gut, you’re influencing your healthspan, or the number of years you live in good health.

An older microbiome age doesn’t necessarily mean illness is present, but it can act as an early warning sign. Addressing it early allows you to make meaningful changes that reduce future health risks.

As awareness around the microbiome grows, many healthcare professionals see it as a central focus for preventative health strategies in the years to come [42] [43] [44].

Final thoughts from Yusra

“Your microbiome age is a powerful reflection of your internal health. While it may differ from your actual age, it can give you insight into how well your body is coping with modern lifestyle demands. The exciting part is that this number isn’t set in stone. Through small, manageable changes, you can actively support your gut and improve your long-term wellbeing. At Vivere, we believe that the key to better health starts from within.”

Vivere helps you take control of your health with personalised insights from state-of-the-art gut microbiome testing, nutritional guidance, science-backed supplements and expert support. Sign up today and start living better, for longer.

Sources

[1] The gut microbiome as a modulator of healthy ageing | Nature Reviews Gastroenterology & Hepatology - Nature

[2] Article Age and the aging process significantly alter the small bowel microbiome - Science Direct

[3] An accurate aging clock developed from large-scale gut microbiome and human gene expression data - PMC

[4] A gut aging clock using microbiome multi-view profiles is associated with health and frail risk - PMC

[5] Counting the Uncountable: Statistical Approaches to Estimating Microbial Diversity - PMC

[6] Species Divergence and the Measurement of Microbial Diversity - PMC

[7] Microbiome 101: Studying, Analyzing, and Interpreting Gut Microbiome Data for Clinicians - PMC

[8] How Microbiomes Affect Skin Aging: The Updated Evidence and Current Perspectives - PMC

[9] The Gut Microbiome, Aging, and Longevity: A Systematic Review - PMC

[10] Unique gut microbiome patterns linked to healthy aging, increased longevity - NIH

[11] Aging through the lens of the gut microbiome: Challenges and therapeutic opportunities - ScienceDirect

[12] Correlation between human gut microbiome and diseases - ScienceDirect

[13] Health and disease markers correlate with gut microbiome composition across thousands of people | Nature Communications

[14] Growing old together: What we know about the influence of diet and exercise on the aging host's gut microbiome - PMC

[15] The Effects of Lifestyle and Diet on Gut Microbiota Composition, Inflammation and Muscle Performance in Our Aging Society - PMC

[16] Nutrition, ageing and the gut microbiota | Feature from King's College London

[17] Mediterranean diet intervention alters the gut microbiome in older people reducing frailty and improving health status: the NU-AGE 1-year dietary intervention across five European countries | Gut

[18] Plant-based diets and the gut microbiome: findings from the Baltimore Longitudinal Study of Aging - ScienceDirect

[19] Early Life Stress and Gut Microbiome Dysbiosis: A Narrative Review - MDPI

[20] Stress Gets into the Belly: Early Life Stress and the Gut Microbiome - PMC

[21] Gut microbiome changes due to sleep disruption in older and younger individuals: a case for sarcopenia? - PMC

[22] Sleep deprivation-induced shifts in gut microbiota: Implications for neurological disorders - ScienceDirect

[23] Sleep Deprivation and Gut Microbiota Dysbiosis: Current Understandings and Implications - PMC

[24] A preliminary examination of gut microbiota, sleep, and cognitive flexibility in healthy older adults - ScienceDirect

[25] Sleep Deprivation Alters Gut Microbiome Diversity and Taxonomy: A Systematic Review and Meta‐Analysis of Human and Rodent Studies - Wiley

[26] The Effects of Lifestyle and Diet on Gut Microbiota Composition, Inflammation and Muscle Performance in Our Aging Society - PMC

[27] Systematic Review of the Effects of Exercise and Physical Activity on the Gut Microbiome of Older Adults - PMC

[28] Effects of exercise frequency on the gut microbiota in elderly individuals - PMC

[29] Antibiotics and the gut microbiome: Understanding the impact on human health - ScienceDirect

[30] Antibiotics, birth mode, and diet shape microbiome maturation during early life - PMC

[31] Current understanding of antibiotic-associated dysbiosis and approaches for its management - PMC

[32] Obesity, Early Life Gut Microbiota, and Antibiotics - PMC

[33] The interaction between smoking, alcohol and the gut microbiome - ScienceDirect

[34] The Gastrointestinal Microbiome: Alcohol Effects on the Composition of Intestinal Microbiota - PMC

[35] Effect of Cigarette Smoke on Gut Microbiota: State of Knowledge - PMC

[36] Smoking and microbiome in oral, airway, gut and some systemic diseases | Journal of Translational Medicine

[37] Smoking has disruptive effects on the small bowel luminal microbiome | Scientific Reports

[38] Microbiota based personalized nutrition improves hyperglycaemia and hypertension parameters and reduces inflammation: a prospective, open label, controlled, randomized, comparative, proof of concept study - PubMed

[39] Rethinking healthy eating in light of the gut microbiome - ScienceDirect

[40] Effects of a personalized nutrition program on cardiometabolic health: a randomized controlled trial | Nature Medicine

[41] Personalized Nutrition Through The Gut Microbiota: Current Insights And Future Perspectives - Oxford Academic

[42] Harnessing gut microbiota for longevity: Insights into mechanisms and genetic manipulation - Shi - 2024

[43] Microbiome-based therapeutics towards healthier aging and longevity | Genome Medicine | Full Text

[44] Healthy gut, healthier aging - Harvard Health

Author
Scott Weaver Medical Content Writer

Scott Weaver

Medical Content Writer

Scott is a professional content writer with more than four years of experience specialising in medical content. He always aims to produce clear, informative and reliable health and well-being-based content that readers can trust. He has covered a wide range of topics on a number of different medical conditions and treatments, both conventional and holistic. The aim of Scott’s work is to provide readers with the information they need to get a better understanding of their health and well-being. Outside of work, Scott enjoys cooking, travelling and watching sports – especially football, cricket and American football.
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Medical Reviewer
Yusra Serdaroglu Aydin - Head of Nutrition & Registered Dietitian at Vivere

Yusra Serdaroglu Aydin, MSc RD

Head of Nutrition and Registered Dietitian

Yusra is a registered dietitian with a multidisciplinary background in nutrition, food engineering, and culinary arts.

During her education, her curiosity about all aspects of food led her to earn an Associate Degree in Culinary Arts and an MSc in Food Engineering. She explored the kitchen side to create recipes that are both healthy and delicious, while gaining a deep understanding of the technologies, regulations, and strategies behind the food we eat in the modern world.

She has over five years of experience helping people modulate their gut microbiome, improve gastrointestinal health, optimize blood parameters, manage food intolerances, and achieve sustainable weight management. She has worked with thousands of patients, helping them transform their long-term eating habits, and is deeply passionate about improving nutrition knowledge and habits in those she supports.

At Vivere, Yusra leads the development and continuous improvement of nutrition-focused products and services. Her work involves aligning scientific research with product strategy, enhancing user experience, and supporting cross-functional collaboration. With experience in business development and training, she brings a practical, science-based approach to creating effective, health-oriented solutions.

Outside of work, Yusra loves to cook for loved ones, enjoy good food, travel to explore new cuisines, and seek out local dishes to bring fresh flavors to the table.

Education:
Health Science University -  BSc Nutrition and Dietetics, 2020
Anadolu University -  Associate Degree in Culinary Arts, 2019
Istanbul Technical University - MSc Food Engineering, 2024

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