NAD Therapy

NAD therapy

What is NAD therapy?

NAD therapy is a treatment that aims to boost the levels of a natural molecule in your body called Nicotinamide Adenine Dinucleotide (NAD+). This molecule is vital for turning the food you eat into energy and for helping your cells repair themselves. As you get older, your body’s NAD+ levels naturally drop, which can lead to tiredness, slower recovery, and other signs of ageing. NAD therapy helps to restore these levels, often through an intravenous (IV) infusion.

What is NAD+?

NAD+ is a coenzyme found in every cell in your body. It helps your body’s cells produce energy, supports brain function, and plays a key role in DNA repair [1]. Think of it as the body’s natural battery charger; it keeps your cells running smoothly so they can perform at their best.

How NAD therapy works

NAD therapy usually involves an IV drip that delivers NAD+ directly into your bloodstream. By bypassing the digestive system, this method allows your body to absorb the molecule more efficiently. Once inside your cells, NAD+ helps improve energy production and supports your body’s natural repair processes.

In recent times, DIY therapy options have become available in the form of subcutaneous injections, this allows people to supplement NAD+ at home through an easy to administer NAD injection.

The table below compares how NAD IV drip therapy compares to at-home NAD injection therapy.

Feature IV Drip Therapy At-Home Injections (Subcutaneous)
Administration Intravenous (requires a professional) Subcutaneous (DIY / Self-administered)
Location Clinic / Hospital Home
Absorption Direct to bloodstream (bypasses digestion) High bioavailability (bypasses digestion)
Best For Clinical supervision, high-dose needs Convenience, regular maintenance, privacy

Learn how Vivere's NAD injection compares to other suppliers NAD+ shots and why people across the UK are choosing at-home NAD+ therapy in major cities such as:

Common reasons for trying NAD therapy

Primary Benefit Target Area Potential Outcome
Energy Boost [2] Cellular Energy Relief from fatigue, burnout, and an indirect link to improving testosterone production.
Brain Health [3] Cognitive Function Enhanced focus, memory, and mental clarity.
Ovarian Support [4] Reproductive System Improved fertility outcomes and hormone regulation.
Anti-Ageing [5] DNA & Cells Cellular repair and reduction of oxidative stress.
Recovery Aid [6] Systemic / Gut Support for detox programs and microbiome balance. It can contribute to improving digestive problems and microbiome imbalances

Potential benefits and considerations

People who try NAD therapy often report feeling more energised, focused, and refreshed. However, as with any health treatment, results can vary depending on your individual health and lifestyle. It’s important to speak to a qualified healthcare professional before starting NAD therapy, especially if you have any existing health conditions.

Possible side effects

NAD therapy is generally considered safe when administered by trained professionals. Some people may experience mild side effects such as nausea, dizziness, or slight discomfort during the infusion. These effects are usually short-lived.

Who might benefit from NAD therapy?

NAD therapy may be suitable for adults looking to improve energy levels, enhance focus, or support healthy ageing. It may also be considered by those recovering from physical or mental stress. Always consult a healthcare professional to check if it’s appropriate for you.

Nutritionist's Corner: Final Thoughts

“NAD therapy can be a useful way to support your body’s natural energy systems, especially if your lifestyle or age is causing low energy levels. However, it’s not a magic fix. Balanced nutrition, good sleep, hydration, and regular exercise are just as important for keeping your NAD+ levels healthy.”
- Yusra Serdaroglu Aydin, MSc RD

Vivere helps you take control of your health with personalised insights to optimise your microbiome from our state-of-the-art gut testexpert-led nutritional guidance, science-backed supplements, including our NAD+ injection and expert support. Join today and start living better, for longer. 

Sources:

[1] Braidy N, Liu Y. NAD+ therapy in age-related degenerative disorders: A benefit/risk analysis. Exp Gerontol. 2020 Apr;132:110831. doi: 10.1016/j.exger.2020.110831. Epub 2020 Jan 7. PMID: 31917996.

[2] Yusri, K., Jose, S., Vermeulen, K.S. et al. The role of NAD+ metabolism and its modulation of mitochondria in aging and disease. npj Metab Health Dis 3, 26 (2025). https://doi.org/10.1038/s44324-025-00067-0

[3] Zhao Y, Zhang J, Zheng Y, Zhang Y, Zhang XJ, Wang H, Du Y, Guan J, Wang X, Fu J. NAD+ improves cognitive function and reduces neuroinflammation by ameliorating mitochondrial damage and decreasing ROS production in chronic cerebral hypoperfusion models through Sirt1/PGC-1α pathway. J Neuroinflammation. 2021 Sep 16;18(1):207. doi: 10.1186/s12974-021-02250-8. PMID: 34530866; PMCID: PMC8444613.

[4] Liang J, Huang F, Song Z, Tang R, Zhang P, Chen R. Impact of NAD+ metabolism on ovarian aging. Immun Ageing. 2023 Dec 2;20(1):70. doi: 10.1186/s12979-023-00398-w. PMID: 38041117; PMCID: PMC10693113.

[5] McReynolds MR, Chellappa K, Baur JA. Age-related NAD+ decline. Exp Gerontol. 2020 Jun;134:110888. doi: 10.1016/j.exger.2020.110888. Epub 2020 Feb 22. PMID: 32097708; PMCID: PMC7442590.

[6] Dehhaghi M, Panahi HKS, Kavyani B, Heng B, Tan V, Braidy N, Guillemin GJ. The Role of Kynurenine Pathway and NAD+ Metabolism in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Aging Dis. 2022 Jun 1;13(3):698-711. doi: 10.14336/AD.2021.0824. PMID: 35656104; PMCID: PMC9116917.

 

Author
Yusra Serdaroglu Aydin - Head of Nutrition & Registered Dietitian at Vivere

Yusra Serdaroglu Aydin, MSc RD

Head of Nutrition and Registered Dietitian

Yusra is a registered dietitian with a multidisciplinary background in nutrition, food engineering, and culinary arts. During her education, her curio...