Is Injecting NAD+ Safe? A Beginner’s Guide to Home Therapy
Last Updated: 12 January 2026

Yes, injecting NAD+ at home is safe if you use a reputable provider like Vivere. Unlike unregulated powders from overseas, Vivere’s NAD+ is manufactured in a UK-based sterile facility. The "injection" is actually a simple, nearly painless click-pen system, similar to insulin and weight loss injections, designed specifically for easy self-administration at-home without professional medical training.
Key Takeaways
It is Legal: Vivere is the only UK provider guaranteed sterile manufacturing in a UK facility.
No "Hospital Needles": We use a pen with a tiny 6mm microneedle (thinner than an eyelash).
Precision Dosing: The pen allows precise dosing to avoid side effects like the nausea common with IV drips.
Painless Process: Most users describe the sensation as a "mosquito bite" or feel nothing at all.

Everything you need to know about injecting NAD+ at home
The idea of injecting yourself can be scary.
It is completely normal to feel nervous. Most of our customers felt exactly the same way before their first order. You probably associate needles with hospitals, blood tests and pain.
Subcutaneous NAD+ Therapy is different. It is not a medical procedure you endure. It is a 10-second morning ritual, as easy as brushing your teeth.
This guide will walk you through exactly why it is safe, how the "pen" works and why thousands of people have swapped their pills for injections.
Is it legal and safe in the UK?
Yes. However, quality varies wildly.
The internet is full of "grey market" NAD+ vials shipped from overseas with no safety checks. This is where the danger lies.
NAD+ injections are generally safe when sourced from reputable providers [1]. Vivere is different. We are the only NAD+ provider in the UK to manufacture our product using an NHS-approved, UKAS-accredited partner.
GMP Certified: Good Manufacturing Practice guaranteed.
Endotoxin-Free: Rigorously tested to ensure no bacterial contamination.
NHS-Approved Partners: Our distribution partners are trusted by the NHS.
When you buy Vivere, you aren't buying a "supplement." You are buying a medical-grade product.
How the Pen Works (The "Click" System)
The Vivere system is a pen.
How to use it:
Dial: You twist the end of the pen to select your dose.
Touch: You place the flat end against your skin.
Click: You press the button. The pen does the rest.
Does it hurt?
This is one of the most common questions we get.
The honest answer: It feels like a tiny pinch.
The needle is a microneedle. It is only 6mm long and incredibly thin (31 gauge).
Because you are injecting into fatty tissue (not muscle), there are very few nerve endings. Many of our customers are surprised to find they don't feel it at all.
Where do I inject?
You need a "fatty" area. The two best spots are:
The Stomach: At least two inches away from your belly button.
The Thigh: The top outer part of your leg.
You simply pinch an inch of soft tissue to create a cushion, place the pen against it, and click.
Storing your NAD+
NAD+ is a fragile molecule.
The Golden Rule: Keep it in the fridge.
Temperature: Store between 2°C and 8°C.
Shelf Life: Once opened, a cartridge lasts about 30 days.
Left Out? If you accidentally leave it on the counter overnight, don't panic. It is stable for short periods, but put it back in the fridge immediately to stop it from degrading.
Common Side Effects
NAD+ is a potent molecule. If you inject too much, too fast, you might feel:
Mild Nausea: A "queasy" stomach for 5-10 minutes.
Flushing: A warm sensation in your face or chest.
Headache: A dull ache (rare).
The Solution: The best way to avoid side effects is to follow all of the usage instructions carefully and ensure you are only using the recommended dose (15 units on the Vivere pen).
Fear is the only barrier
Injections work better than pills. The only thing stopping most people is the fear of the needle.
But once you hear that first "click" and realise it didn't hurt, the fear vanishes. All that is left is the energy you have been waiting for.
Nutritionist's Corner: Final Thoughts
"Safety in supplementation comes down to purity and protocol. Our production partner ensures that you are injecting sterile NAD+ that is free from endotoxins, something that unregulated powders cannot guarantee. Home injection is a safe, manageable and highly effective way to support long-term metabolic health."
Vivere helps you take control of your health with personalised insights from state-of-the-art gut microbiome testing, nutritional guidance, science-backed supplements, NAD injections and expert support. Sign up today and start living better, for longer.
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Author

Yusra Serdaroglu Aydin, MSc RD
Head of Nutrition and Registered Dietitian
Yusra is a registered dietitian with a multidisciplinary background in nutrition, food engineering, and culinary arts. During her education, her curio...